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JACC journal series to provide in-depth review of effect of COVID-19 on the heart

The Journal of the American College of Cardiology has issued a three-part focus seminar on COVID-19 to address the complex relationship between COVID-19 and the heart. The seminar will review “coronavirus and cardiometabolic syndrome”, “coronavirus historical perspective, disease mechanisms, and clinical outcomes”, and “coronavirus and cardiovascular disease, myocardial injury and arrhythmia”.

Regarding the arrhythmia paper, Dr Sean P Pinney (University of Chicago, Chicago, USA) and colleagues discuss the underlying mechanisms producing cardiovascular damage among hospitalised patients with severe COVID-19 infection—including that of thromboembolic disease and arrhythmia. They report that myocardial injury occurs in about one-quarter of hospitalised COVID-19 patients and is associated with a greater need for mechanical ventilator support and higher hospital mortality. Dr Pinney comments: “Myocardial injury results in detectable increases in serum troponin, varying degrees of ventricular dysfunction and relatively frequent cardiac arrhythmias. Whether these effects are simply associated with poor patient outcomes, including death, or directly contribute to patient mortality is as yet uncertain.”

For more information on COVID-19, view our COVID-19 resources page.

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